Abstract |
---|
Production of L-aspartic acid from Brevibacterium by the cell re-using process. |
|
Strong aspartase activity was found in cells of Brevibacterium genus, having resistance to alpha-amino-n-butyric acids, and the production
of L-aspartic acid from fumaric acid was studied by reusing intact cells.
The properties of intracellular aspartase were also investigated. In order
to produce the L-aspartic acid at high yield, the conditions which suppressed
the unwanted formation of L-malic acid were determined. The production of L-aspartic acid was carried out reusing intact cells which suppressed the side reaction, and L-aspartic acid was produced from fumaric acid stoichiometrically. |